This new range of intelligent reactor systems based upon COFLUX technology will revolutionise drug development and allow faster scale-up through to production. For the first time, accurate, usable calorimetric data can produce meaningful information during process development - a key parameter for any PAT initiative, as processes are scaled-up.
These systems provide effective process analytics in the form of enthalpy, power and heat transfer coefficient enabling a clear and accurate measure of the status and progress of any reaction.
This ability to view the whole process as it happens/develops, instead of relying on snapshots of analytical data or waiting for samples to return from the lab, delivers immediate benefits in the form of process understanding and reduced development time.
Confidently predicting how a process will behave using traditional reactor design has presented many problems primarily caused by the lack of information that these systems provide.
By using this new technology to precisely control key process parameters such as crystallisation points, end point detection and the timing of additions and nutrients ensures that consistently achieving quality products and maximising yields becomes a matter of routine.
Key business benefits of adopting ChemFlux technology include:
Non intrusive real-time monitoring of reaction & crystallisation processes
Increased process understanding & optimisation
Reduced batch to batch variability, rejects & failures
Reaction / process fingerprinting
Improved yield & endpoint detection
Reduced drug development costs
Reduced development times, getting drugs to market faster