Managing Complex Equipment Status in a GMP Environment
Batch manufacturing systems must maintain the status of equipment, including which are available, dirty, out of service, etc. In industries that enforce Good Manufacturing Practices (GMPs), additional status types and values for process equipment must be maintained. Rules associated with the equipment status can be complex and involve the equipment class, current equipment state and time in the current
state. This paper covers the operator interface used to review the equipment status and the interlocking requirements between the recipe and batch phases based on multiple status types.
De-bottlenecking A De-iso-butanizer With VG-Plus High Performance Trays
To maximize a plants performance, it is critical to fully understand the equipment being used, their mechanisms of operation, limitations and capabilities. This includes furnaces, exchangers, pumps, and mass transfer devices for distillation columns: fractionation trays, random and structured packing and associated liquid and vapor distributors. The purpose of this paper is to provide an overview of the key factors to successfully revamp with the goal of maximizing capacity without compromising efficiency.
Use CFD to Improve Crystallization | Chemical Processing
In this article, Kumar Dhanasekharan, Ph.D., technical specialist with the computational fluid dynamics (CFD) specialist Fluent, Inc., shows how modelling crystallizers using CFD can help improve process understanding, control crystal size distribution (CSD) and improve pharmaceutical crystallization results.
Aseptic PAT and Particle Monitoring
In this white paper, Mark Hallworth, pharmaceutical manager for Particle Measuring Systems, discusses continuous monitoring methods, how theyre evolving, and why theyre important.
PACs for industrial control: The future of control
With a number of vendors producing Programmable Automation Controllers that combine the functionality of a PC and reliability of a PLC, PACs today are increasingly being incorporated into control systems. This white paper explores the origins of the PAC, how PACs differ from PLCs and PCs, and the future direction of industrial control with PACs.
Hygienic Feeder Design
Specifying a hygienic bulk solids feeder is not a simple task. The wide variety of requirements needed
for specific applications are similar in scope to explosion proof environmental requirement variations.
Level measurement of bulk solids and powders
This 26-page white paper from Monitor Technologies discusses the difficulties in measuring bulk solids and powders in bins, silos and hoppers. Download this document to learn which technologies are out there that can make this job easier.
Audit Your Materials Handling
This 5-page document discusses how to improve the return on investment by appropriate auditing of materials-handling operations.
Design Guidelines for Distillation Columns in Fouling Service
This 33-page paper discusses the wide variety of factors that can cause fouling and the impact of this fouling on the performance of a distillation column. It then provides details on practical methods for mitigating fouling, including equipment design, surface treatment, and use of additives.