Oxygen in cell culture/venting ozonated vessels
This white paper outlines trends and opportunities for gasket standardization in processing plants ... including the potential for more reliable sealing, cost savings, inventory reduction, easier installation and safety practices. Steps are outlined for achieving success in gasket standardization across steel, glass-lined and FRP piping.
Applying ISA-S88 to Software Migration Engineering
Dow Chemical maintains thousands of batch control systems world-wide built on its proprietary MOD 5 computer system. Over decades, they have been meticulous to preserve and enhance these systems. Dow intends to preserve and reap the rewards of this diligence by developing reverse engineering best practices and tools to migrate this intellectual property to next-generation platforms.
Process Moisture Analysis using FT-NIR
Manufacturing a pure product can be critically important to the next steps in the manufacture of a powder-based product. As a result the removal of residual moisture and solvents from the crystallization, filtration and drying steps can be crucial to producing a stable product.
Managing Complex Equipment Status in a GMP Environment
Batch manufacturing systems must maintain the status of equipment, including which are available, dirty, out of service, etc. In industries that enforce Good Manufacturing Practices (GMPs), additional status types and values for process equipment must be maintained. Rules associated with the equipment status can be complex and involve the equipment class, current equipment state and time in the current
state. This paper covers the operator interface used to review the equipment status and the interlocking requirements between the recipe and batch phases based on multiple status types.
Guidance note for environmental safety instrumented systems
Safety Instrumented Systems (SIS) are designed to monitor the process and control outputs to prevent or mitigate hazardous events. The design process strives for inherent safety, which is enhanced by applying multiple independent safety layers. Learn how to prevent accidents with prevention layers and minimise the consequences with mitigation layers.
Securing Batch Control Systems
Batch process control security is becoming a critical concern for the process control domain, IT technology infrastructure and the business enterprise. This paper explores several key security concerns in batch control system architectures and methods for addressing these issues.
Preventing Segregation During Powder Drying
This 4-page case history by Jeroen van den Berg of Bolz-Summix discusses how changing process conditions within a conical screw dryer eliminated granulation and minimized product segregation.
White Paper: Internet Access in a Process Control Environment
Industrial automation is no longer limited by the walls of a production facility. More and more automation is being handled via remote communication, whether its from the office or from the comfort of your own home. Todays PLCs give you the ability to access your control system to
handle such tasks as monitoring via a website to determine the condition of a machine or check other statistics.
Wago Innovative Connections
Clean-in-place operation for thin-cake filtration technologies
This article discusses the choice of thin-cake (2 25 mm) separation technologies and their benefits to optimizing the effectiveness of the production process. The paper continues with a
discussion of clean-in-place operations to meet current Good Manufacturing Practices (cGMP) guidelines including riboflavin test and validations.
Chemical Hazard Communication
Under the provisions of the Hazard Communication Standard,
employers are responsible for informing employees of the
hazards and the identities of workplace chemicals to which
they are exposed.
Cybersecurity: Power Industry Locks Down
The power industry is susceptible to a variety
of cyber threats, which can wreak havoc on control systems. Management, engineering and IT must commit to a comprehensive approach that encompasses threat prevention,
detection and elimination.
Process Control Network Security
This document provides an understanding of intrusion detection and prevention systems, why they are necessary, how and where they fit in the control system environment, and gives example scenarios.
Use CFD to Improve Crystallization | Chemical Processing
In this article, Kumar Dhanasekharan, Ph.D., technical specialist with the computational fluid dynamics (CFD) specialist Fluent, Inc., shows how modelling crystallizers using CFD can help improve process understanding, control crystal size distribution (CSD) and improve pharmaceutical crystallization results.
Fieldbus and remote I/O system comparison
Nine manufacturers participated in the FuRIOS study, which was conduced under the lead of an end user company that compared its use of fieldbus and remote I/O in full detail.