A mini-plant study helps to demonstrate the required separation, to develop an accurate process simulation and to further refine and optimize the operation to maximize productivity (the mass of desired product attained per unit volume of separation media) and minimize solvent consumption (mass or volume of solvent consumed per unit mass of product) . We've successfully used this strategy to evaluate and optimize the protein separation cited earlier and to evaluate a number of proprietary applications.
Initial feasibility often can be assessed in a week or two of pulse test work; subsequent mini-plant work can be completed in one or two months, providing sufficient information to develop budgetary estimates of capital and operating costs for a large-scale installation.
BRUCE PYNNONEN is a senior applications specialist and SHAWN FEIST is a lead engineer with Dow Water and Process Solutions, Midland, Mich. YOGESH HASABNIS is a senior engineer in the Engineering & Process Sciences Laboratory at Dow's Research Center in Pune, India. DAVE ALBERS is a research scientist in Dow's Analytical Sciences Laboratory in Midland. TIMOTHY FRANK is a fellow and senior technical manager at Dow's Engineering Sciences Laboratory in Midland. Contact them via firstname.lastname@example.org.
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